Sentra Biosains Dinamika

ViennaLab - β-Globin StripAssay® SEA

Catalog No. 4-150 Category

Thalassemias are characterized by inherited defective hemoglobin synthesis leading to microcytic, hemolytic anemias. The clinical heterogeneity ranges from asymptomatic to very severe forms requiring regular blood transfusions. Globin StripAssays® detect common thalassemia-causing genetic variants worldwide, and the β-Thal Modifier StripAssay® identifies co-inherited variants known to ameliorate severity of beta-thalassemia.


  • Severe thalassemia is life-limiting and poses a major public health burden in Mediterranean countries, Africa, the Middle East, South-East Asia, and the Indian subcontinent.
  • Mutations in the alpha- and beta-globin genes lead to reduced or abolished globin-chain synthesis or cause structurally abnormal hemoglobin.
  • Genetic analysis is required to confirm the clinical diagnosis and is indispensable for genetic counseling.
  • Apart from bone marrow transplantation, no ultimate cure is available up-to-date. However, identifying favourable genetic modifiers in patients help to predict the severity of beta-thalassemia phenotypes.

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