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Amino Acid Analyzer System
The gold standard dedicated Amino Acid Analyser for in vitro diagnostic use and research
A proven instrument for the precise quantification and qualification in free amino acids of physiological fluids,quantifying amino acids in inborn errors of metabolism, including Phenylketonuria, the technique complies with the new In Vitro Diagnostic Regulatory (IVDR) requirements. The Bio 30+ System is a gold standard dedicated amino acid Analyser used by reference laboratories, hospitals, pharmaceutical and industrial labs worldwide.
Reproducibility Area | Better than 1.5% RSD at 10 nanomoles. Retention time: better than 0.5% RSD. |
Limit of Detection | 9 – 15 pmoles (primary amino acids detection at 570nm) |
Time of analysis | Accelerated analysis: 115 min injection to injection |
(based on the separation of 45 physiological amino acids) | High Performance analysis: 170 min injection to injection |
Analytical Column | High pressure PEEK column packed with Ultropac 8 cation exchange resin. Peltier heating/cooling system. |
Eluent System | 6 buffer system (5+1 regeneration solution) stored on the instrument at room temperature in graduated 1L glass |
bottles under nitrogen pressure. Ninhydrin reagent: Stored on the instrument at room temperature under nitrogen | |
pressure in a 2L plastic coated glass bottle. | |
Temperature | Column temperature variable between 20°C and 99°C. Reaction Coil temperature adjustable between 40°C and |
145°C (optimal temperatures: 135°C for UltraNin, 138°C for EZ Nin). | |
Photometric | Detection Single flow cell with optical beam splitter. Dual channel detection at 440nm and 570nm. |
5000μL. 200μL loop supplied as standard. | |
Software | BioSys control software |
Biochrom Alias Manager autosampler control software | |
OpenLAB CDS EZChrom Edition | |
Dimensions and Weights | Bench top fluidics cabinet: 48 x 59 x 57 cm, 19 x 23 x 22 inches (w x d x h) |
– Weight: 50 kg, 110 lbs | |
– Autosampler: 30 x 57.5 x 36 cm, 12 x 23 x 14 inches (w x d x h) | |
– Weight: 21 kg, 46 lbs | |
Operating Conditions | Operating temperature: 15 °C to 25 °C |
Maximum humidity: 80% at 25 °C | |
Required Services | Oxygen free nitrogen gas (99.99%) or Argon regulated to 73.5 psi (5bar). |
Drainage facility. | |
240V/100V, 50Hz/60Hz, 300 VA mains supply. | |
Safety System | Automatic shut-down and reaction coil flushing in the event of: |
• photometer lamp failure | |
• incorrect ninhydrin / buffer / coil / nitrogen pressures | |
• incorrect coil and column temperatures | |
• power failure |
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