Sentra Biosains Dinamika

Berthold - FlowStar LB 514

Catalog No. 62777-10 Category


In the FlowStar² LB 514 ultimate sensitivity has been combined with touch-screen technology for quick and easy operation. Designed for maximum ease of use, safety and flexibility, the FlowStar² LB 514 sets the new standard for what a radio-HPLC flow detector should be. With over 50 years of experience Berthold Technologies is taking radio-HPLC flow detection to the next level. A wide range of available cells ensures optimal performance and supports full compatibility with both, routine and challenging applications. The convenient dual mode capability enables simple installation in different configurations and makes integration into existing systems easy.

User friendly

The FlowStar² LB 514 is designed to be intuitive and easy to use, to get you up and running quickly. The intuitive touch screen interface makes it easy to get started and keep going. Results are displayed in both, a graphical chromatogram and a numerical format, so you can start interpreting your results in real time while the run is still in progress.

The FlowStar² frees you from configuring parameters manually, thanks to the use of SmartCells: all measuring cells are equipped with a chip to automatically set the correct cell-specific system parameters. In addition, the software includes an extensive isotope library with predefined energy windows and cell usage options (14C, 3H, 32P, 33P, 35S, 128I, 111In, 99mTc…).

Easy integration into your HPLC system

The FlowStar² LB 514 makes integration easy so that everything works together to ensure consistent and reliable results. The integrated A/D converter records signals from external instruments (e.g. UV-detector) without requiring expensive additional hardware, while the USB port enables external control using RadioStar or other HPLC control software (e.g. Chromeleon™).

In addition, the dual analog output allows for the convenient integration into existing HPLC data systems.

The FlowStar² supports UHPLC and other LC technologies:

  • HPLC-MS (Mass Spectrometry)
  • HPLC-NMR (Nuclear Magnetic Resonance)

Safe and secure

The FlowStar² LB 514 embodies our commitment to providing everything you need for safe and easy integration into your lab environment.

Safety features:

  • Automatic HV shutdown for system safety.
  • Built-in leak detection to prevent the measuring system from damage caused by aggressive liquids. The system will shut down automatically in the event of cell leakage.

Security features:

  • On-board system performance tests with instrument-based history function.
  • Password-based multi user access control to protect instrument from unauthorised use.


  • Several test cells are available to perform periodic system performance tests. These cells have been developed to meet GLP/GMP requirements and to guarantee a continuous system performance.

High sensitivity

The FlowStar² is the ultimate platform for high-sensitivity radio-HPLC flow detection. It uses random coincidence counting and luminescence subtraction for ultimate performance. In addition, the integrated spectrum scanning feature provides improved optimisation of detector setup for each isotope.

Easy-to-use software for maximum productivity

The RadioStar software combines the ability to run sophisticated measurements with a user-friendly operation and user interface. In addition, a Chromeleon™ driver is available. Chromeleon™ is known as a very versatile chromatograpy software package supporting many different hardware solutions. The driver is fully certified, digitally signed by Thermo Scientific™ and runs with versions 6.x and 7.x.

Measuring cells specific to your needs

Choose from a wide range of available SmartCells to meet your application needs. These high sensitivity cells are equipped with a SmartChip to automatically set the correct cell-specific system parameters. The automatic shut-down feature of the system after removal of a cell from the detector provides additional safety.

The range of SmartCells include:

  • Liquid scintillation (admixture) cells
  • Solid scintillator cells
  • Gamma isotopes and Positron Emitter (PET) cells
  • Cells for preparative SFC
  • Microbore cells for UHPLC and UPLC™
  • Special Iodine Cells (125I)
  • Cherenkov cells for high energy beta emitters



Detection unit12 x 1.25” borehole NaI crystal with photomultiplier tube
Lead shielding6 mm lead shielding surrounding each detector, that is 12 mm lead between the detectors
Detector crosstalk0.413 % for 51Cr
Energy Range10-510 KeV
Isotopes125I, 57Co, 51Cr, 99Tc; plus, any other radioisotope within the energy range
Efficiency75% for 125I
Tube formatØ 14.5 mm in rack; Ø 16 mm in borehole
CPM raw dataSingle or dual channel
CPM ratioRAST, Cr-Release, T3 Uptake
RIAe.g. FT4, single or dual channel
IRMAe.g. TSH, single or dual channel
Combined RIA/CPM ratioe.g. FTI
Combined RIA/IRMAe.g. FT4/TSH
Receptor Bindinge.g. ER
Assay QCBased on intra assay controls
Instrument QCDetector efficiency, standardisation, background
Several options available:
Embedded RIA software (stand-alone mode)
LBIS Windows PC Immunoassay Software
MikroWin Software
InterfaceSerial RS 232
Power Supply220 V / 50 Hz or 110 V / 60 Hz (depending on model)
Temperature range
Storage 0-40° C
Operation 15-35° C
Humidity10-85%, non-condensing
RegulationsCE, UL, CSA
Dimensions (W x D x H)395 x 510 x 235 mm
Weight39 kg



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