Sentra Biosains Dinamika

ViennaLab - EGFR XL StripAssay®

Mutations in the epidermal growth factor receptor (EGFR) gene are predictive of the response to EGFR tyrosine kinase inhibitor (TKIs) therapies. The ViennaLab StripAssay® identifies 30 EGFR mutations relevant for non-small cell lung cancer (NSCLC) TKI therapies.

EGFR

  • NSCLC comprises approximately 85% of all lung cancers. Tumor specimens from patients should be tested for the presence of EGFR mutations prior to TKI treatment.
  • Patients carrying EGFR mutations known as `activating mutations´ may benefit from first- or second- or third-generation TKIs. Patients carrying the `resistance mutation´ EGFR T790M may benefit from third-generation TKI.
  • The EGFR XL StripAssay® is designed to assist clinicians in the stratification of patients considered for TKI therapy.

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